Simple and specific test for measuring lipid peroxides in plasma.

Simple and specific test for measuring lipid peroxides in plasma.

The specificity of an iodometric assay for measuring lipid peroxides in lipoproteins was tested, compared with the fluorimetric thiobarbituric acid assay, and adopted for detecting lipid peroxide in plasma samples. Oxidation of low density lipoproteins in vitro by Cu2+, lipoxidase, and phagocytosing polymorphonuclear leucocytes was sensitively detected by the iodometric assay. Unlike the thioba...

Modification of simple and specific test for measuring lipid peroxides in plasma.

Plasma levels of lipid peroxides in patients with Parkinson's disease.

Oxidative stress is implicated as a major factor for nigral neuronal cell death. Metabolic failure in antioxidant mechanisms could hypothetically facilitate the chemical processes that lead to lipid peroxidation. To elucidate whether elevated lipid peroxidation rates might increase risk of developing Parkinson's disease (PD), the Authors determined plasma levels of malondialdehyde (MDA) in 80 P...

Hormonal contraceptive increases plasma lipid peroxides in female rats. Relationship to platelet aggregation and lipid biosynthesis.

We investigated whether changes in plasma oxidative properties could occur after oral (hormonal) contraceptive (OC) administration in female rats and whether such changes could be responsible for the platelet increase in aggregation and lipid biosynthesis observed with that treatment. Platelets and plasma (platelet-poor) from control and OC (ethinyl estradiol + lynestrenol)-treated rats were pr...

Simple specific test for urine glucose.

ROCEDURES FOR THE DETECTION OF SUGAR IN URINE are among the oldest tests known in clinical chemistry. Legends going back to earliest times describe the attraction of insects to urine containing sugar. In many instances it is difficult to separate legend from reality in tracing the history of tests for glycosuria. Among such pioneer American clinical chemists as Stanley Benedict, Otto Folin, Vic...